TargetMol

ML115

Product Code:
 
TAR-T35544
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35544-1mg1mg£148.00
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Quantity:
TAR-T35544-5mg5mg£262.00
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TAR-T35544-10mg10mg£374.00
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TAR-T35544-25mg25mg£603.00
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TAR-T35544-50mg50mg£816.00
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Quantity:
TAR-T35544-100mg100mg£1,075.00
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Quantity:
TAR-T35544-200mg200mg£1,420.00
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Quantity:
TAR-T35544-500mg500mg£2,062.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.
CAS:
912798-42-6
Formula:
C15H15ClN2O4
Molecular Weight:
322.75
Pathway:
JAK/STAT signaling; Stem Cells
Purity:
0.98
SMILES:
COc1cc(NC(=O)c2cc(on2)C2CC2)c(OC)cc1Cl
Target:
STAT

Documents

References

Li M, et al. Effect of acetate formation pathway and long chain fatty acid CoA-ligase on the free fatty acid production in E. coli expressing acy-ACP thioesterase from Ricinus communis. Metab Eng. 2012 Jul;14(4):380-7. Madoux F, et al. Modulators of STAT Transcription Factors for the Targeted Therapy of Cancer (STAT3 Activators). 2009 Aug 27 [updated 2010 Dec 16]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010?.