TargetMol

Phox-I2

Product Code:
 
TAR-T25952
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25952-1mg1mg£132.00
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TAR-T25952-5mg5mg£230.00
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TAR-T25952-1mL1 mL * 10 mM (in DMSO)£266.00
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TAR-T25952-10mg10mg£309.00
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TAR-T25952-25mg25mg£466.00
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TAR-T25952-50mg50mg£646.00
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TAR-T25952-100mg100mg£864.00
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TAR-T25952-500mg500mg£1,661.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
Phox-I2 is a second-generation p67phox interaction with Rac1 inhibitor, effective in inhibiting reactive oxygen species production by human and murine neutrophils.
CAS:
353495-22-4
Formula:
C18H15N3O4
Molecular Weight:
337.335
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
[O-][N+](=O)c1cccc(c1)C1Nc2ccc(cc2C2C=CCC12)[N+]([O-])=O
Target:
NADPH-oxidase

Documents

References

1. Hagenbuchner J, Scholl-Buergi S, Karall D, Ausserlechner MJ. Very long-/ and long Chain-3-Hydroxy Acyl CoA Dehydrogenase Deficiency correlates with deregulation of the mitochondrial fusion/fission machinery. Sci Rep. 2018 Feb 19;8(1):3254. doi: 10.1038/s41598-018-21519-2. PubMed PMID: 29459657; PubMed Central PMCID: PMC5818531. 2. Mortadza SS, Sim JA, Stacey M, Jiang LH. Signalling mechanisms mediating Zn(2+)-induced TRPM2 channel activation and cell death in microglial cells. Sci Rep. 2017 Mar 21;7:45032. doi: 10.1038/srep45032. PubMed PMID: 28322340; PubMed Central PMCID: PMC5359577.