TargetMol

S-Ruxolitinib

Product Code:
 
TAR-T3066
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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CodeSizePrice
TAR-T3066-2mg2mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3.
CAS:
1160597-27-2
Molecular Weight:
306.37
Pathway:
Chromatin/Epigenetic|JAK/STAT signaling|Angiogenesis|Stem Cells
Purity:
0.9975
SMILES:
N#CCC(C1CCCC1)n2cc(cn2)c4ncnc3nccc34
Target:
JAK

Documents

References

Quintas-Cardama A, et al. Blood, 2010, 115(15), 3109-3117.