TargetMol

TLQP-21 TFA

Product Code:
 
TAR-T38077
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T38077-10mg10mgEnquire
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TAR-T38077-1mg1mgEnquire
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TAR-T38077-5mg5mgEnquire
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  • Further Information
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Further Information

Bioactivity:
TLQP-21 TFA, a vGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 uM; human TLQP-21=68.8uM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions[1][2].
Purity:
98%

Documents

References

1.Elena Bresciani , et al. TLQP-21, A vGF-Derived Peptide Endowed of Endocrine and Extraendocrine Properties: Focus on In vitro Calcium Signaling. Int J Mol Sci. 2019 Dec 24;21(1):130. 2.Cheryl Cero, et al. The TLQP-21 Peptide Activates the G-protein-coupled Receptor C3aR1 via a Folding-Upon-Binding Mechanism. ructure. 2014 Dec 2;22(12):1744-1753.