TargetMol

Mazdutide acetate (2259884-03-0 free base)

Product Code:
 
TAR-T78097L
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T78097L-1mg1mg£142.00
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Quantity:
TAR-T78097L-5mg5mg£289.00
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Quantity:
TAR-T78097L-10mg10mg£436.00
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Quantity:
TAR-T78097L-25mg25mg£662.00
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Quantity:
TAR-T78097L-50mg50mg£1,012.00
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Quantity:
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Mazdutide acetate is a potent co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR), a gastrin-regulating hormone analog.Mazdutide acetate stimulates insulin secretion from mouse pancreatic islets, and can be used in studies of obesity and type 2 diabetes (T2D).
Purity:
98%
Target:
Glucagon Receptor

Documents

References

1.Chen T, et al. The Design and Optimization of Monomeric Multitarget Peptides for the Treatment of Multifactorial Diseases. J Med Chem. 2022 Mar 10;65(5):3685-3705. 2.Jiang H, et al. A phase 1b randomised controlled trial of a glucagon-like peptide-1 and glucagon receptor dual agonist IBI362 (LY3305677) in Chinese patients with type 2 diabetes. Nat Commun. 2022 Jun 24;13(1):3613. 3.Chen Y,et al. 682-P: novel dual glucagon and glucagon-like peptide-1 receptor agonist LY3305677 improves glucose control, reduces body weight, and increases energy expenditure in mice[J]. Diabetes, 2021, 70(Supplement_1).