TargetMol

Lenalidomide 4'-alkyl-C3-azide

Product Code:
 
TAR-T84909
Product Group:
 
Other Biochemicals
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T84909-10mg10mgEnquire
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TAR-T84909-50mg50mgEnquire
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Further Information

Bioactivity:
Lenalidomide 4'-alkyl-C3-azide (compound 4a), a chemically modified version of the orally active immunomodulator lenalidomide, is engineered for the synthesis of PROTACs. This compound, serving as a ligand for the ubiquitin E3 ligase cereblon (CRBN), integrates an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-bearing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups [1].
CAS Number:
2399455-71-9
Purity:
98%

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