TargetMol

TWSG1 Protein, Human, Recombinant (His)

Product Code:
 
TAR-TMPJ-01322
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

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CodeSizePrice
TAR-TMPJ-01322-10ug10ugEnquire
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Quantity:
TAR-TMPJ-01322-1mg1mgEnquire
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TAR-TMPJ-01322-500ug500ugEnquire
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TAR-TMPJ-01322-50ug50ugEnquire
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Twisted Gastrulation Protein Homolog 1 (TWSG1) is a 22 kDa secreted protein that belongs to the twisted gastrulation protein family. Human TWSG1 is synthesized as a 223 aa precursor that contains a 25 aa signal peptide and a 198 aa mature chain. TWSG1 may be involved in dorsoventral axis formation. TWSG1 seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors.TWSG1 can inhibit BMP activity by binding directly to BMP proteins, and can act the anti-BMP function, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. TWSG1 may be an important modulator of BMP-regulated cartilage development, chondrocyte differentiation and thymocyte development.
Molecular Weight:
35 kDa (reducing condition)
Purity:
98%