TargetMol

Pentraxin 2/SAP Protein, Mouse, Recombinant (hFc)

Product Code:
 
TAR-TMPK-00113
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-00113-100ug100ugEnquire
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TAR-TMPK-00113-1mg1mgEnquire
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TAR-TMPK-00113-500ug500ugEnquire
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases. Pentraxin 2/SAP Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is P12246.
Molecular Weight:
50.5 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Nakagawa N, et al. Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease. JCI Insight. 2016 Dec 8;1(20):e87446. doi: 10.1172/jci.insight.87446. PMID: 27942582; PMCID: PMC5135274.