TargetMol

CLEC4A Protein, Human, Recombinant (hFc)

Product Code:
 
TAR-TMPK-00126
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-00126-100ug100ugEnquire
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TAR-TMPK-00126-1mg1mgEnquire
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TAR-TMPK-00126-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy. CLEC4A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is Q9UMR7-1.
Molecular Weight:
46.7 kDa (predicted). Due to glycosylation, the protein migrates to 60-65 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Weng TY, et al. Skin Delivery of Clec4a Small Hairpin RNA Elicited an Effective Antitumor Response by Enhancing CD8 Immunity In Vivo. Mol Ther Nucleic Acids. 2017 Dec 15;9:419-427. doi: 10.1016/j.omtn.2017.10.015. Epub 2017 Oct 26. PMID: 29246320; PMCID: PMC5701806.