TargetMol

HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Product Code:
 
TAR-TMPK-01280
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-01280-100ug100ugEnquire
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TAR-TMPK-01280-1mg1mgEnquire
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TAR-TMPK-01280-500ug500ugEnquire
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Further Information

Bioactivity:
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.54 kDa and the accession number is XP_005571238.1.
Molecular Weight:
69.54 kDa (predicted). Due to glycosylation, the protein migrates to 85-105 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Yonesaka K, et al. Abstract 44: U3-1402, a novel HER3-targeting ADC, and a novel DNA topoisomerase I inhibitor inhibit the growth of non-small cell lung cancer with EGFR mutation[J]. Cancer Research, 2017, 77(13 Supplement):44-44.