TargetMol

BST2 Protein, Cynomolgus, Recombinant (His)

Product Code:
 
TAR-TMPK-01298
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-TMPK-01298-100ug100ugEnquire
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TAR-TMPK-01298-1mg1mgEnquire
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TAR-TMPK-01298-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune response. BST2 expression was significantly increased during porcine epidemic diarrhea virus (PEDV) infection of Vero cells by IRF1 targeting its promoter. Both the BST2 and N protein interacted with the E3 ubiquitin ligase MARCHF8/MARCH8 and the cargo receptor.
Molecular Weight:
13.78 kDa (predicted). Due to glycosylation, the protein migrates to 15-30 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Kong N, et al. BST2 suppresses porcine epidemic diarrhea virus replication by targeting and degrading virus nucleocapsid protein with selective autophagy. Autophagy. 2020 Oct;16(10):1737-1752. doi: 10.1080/15548627.2019.1707487. Epub 2019 Dec 27. PMID: 31868081.