TargetMol

TPSAB1 protein, Cynomolgus, Recombinant (His)

Product Code:
 
TAR-TMPK-01303
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-TMPK-01303-100ug100ugEnquire
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TAR-TMPK-01303-1mg1mgEnquire
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TAR-TMPK-01303-500ug500ugEnquire
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsin?like activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.
Molecular Weight:
28.5 kDa (predicted). The protein migrates to 30-3 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Jackson NE, et al. Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation. J Biol Chem. 2008 Dec 5;283(49):34178-87. 2.Hern?ndez-Hern?ndez L, et al. Increased TPSAB1 Copy Number in a Family With Elevated Basal Serum Levels of Tryptase. Front Med (Lausanne). 2021 Apr 13;8:577081.