TargetMol

Kremen-2 Protein, Cynomolgus, Recombinant (His)

Product Code:
 
TAR-TMPK-01304
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-01304-100ug100ugEnquire
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TAR-TMPK-01304-1mg1mgEnquire
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TAR-TMPK-01304-500ug500ugEnquire
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Further Information

Bioactivity:
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy. Kremen-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.04 kDa and the accession number is XP_005591068.2.
Molecular Weight:
37.04 kDa (predicted). Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Chen B, et al. Knockdown of Kremen2 Inhibits Tumor Growth and Migration in Gastric Cancer. Front Oncol. 2021 Jan 7;10:534095. doi: 10.3389/fonc.2020.534095. PMID: 33489867; PMCID: PMC7817645.