TargetMol

IGFBP-7 Protein, Human, Recombinant (hFc)

Product Code:
 
TAR-TMPK-01371
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-01371-100ug100ugEnquire
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TAR-TMPK-01371-1mg1mgEnquire
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TAR-TMPK-01371-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 53.20 kDa and the accession number is IGFBP-7.
Molecular Weight:
53.20 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Li N, et al. IGFBP-7 inhibits the differentiation of oligodendrocyte precursor cells via regulation of Wnt/β-Catenin signaling.?J Cell Biochem. 2018;119(6):4742-4750. doi:10.1002/jcb.26654.