TargetMol

LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Product Code:
 
TAR-TMPK-01380
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-01380-100ug100ugEnquire
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TAR-TMPK-01380-1mg1mgEnquire
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TAR-TMPK-01380-500ug500ugEnquire
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Further Information

Bioactivity:
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation.? LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 58.92 kDa and the accession number is A0A2K5UKB6.
Molecular Weight:
58.92 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Kobayashi I, et al. Dual role of Jam3b in early hematopoietic and vascular development. Development. 2020;147(1):dev181040. Published 2020 Jan 8. doi:10.1242/dev.181040