TargetMol

EPhA3 Protein, Canine, Recombinant (His)

Product Code:
 
TAR-TMPK-01387
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TMPK-01387-100ug100ugEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-TMPK-01387-1mg1mgEnquire
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TAR-TMPK-01387-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Erythropoietin-producing hepatocellular carcinoma cell surface type-A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude mice. The interaction of AR and SP1 contributes to regulate EPHA3 expression, and the SP1 binding sites (-295~-261) in the EPHA3 core promoter region is crucial to the regulation of EPHA3 expression in response to androgen hormone stimuli.
Molecular Weight:
58.97 kDa (predicted). Due to glycosylation, the protein migrates to 60-65 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Diao X, Chen X, Pi Y, Zhang Y, Wang F, Liu P, Gao Y, Wang X, Yang S, Lu S. Androgen receptor induces EPHA3 expression by interacting with transcription factor SPOncol Rep. 2018 Aug;40(2):1174-1184. doi: 10.3892/or.2018.6503. Epub 2018 Jun 18. PMID: 29917167.