TargetMol

GUCY2C Protein, Canine, Recombinant (aa 21-430, His)

Product Code:
 
TAR-TMPK-01388
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-01388-100ug100ugEnquire
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TAR-TMPK-01388-1mg1mgEnquire
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TAR-TMPK-01388-500ug500ugEnquire
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Further Information

Bioactivity:
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Canine, Recombinant (aa 21-430, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.6 kDa and the accession number is F1PAG3.
Molecular Weight:
47.6 kDa (predicted). Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Magee MS, et al. Human GUCY2C-Targeted Chimeric Antigen Receptor (CAR)-Expressing T Cells Eliminate Colorectal Cancer Metastases. Cancer Immunol Res. 2018;6(5):509?516. doi:10.1158/2326-6066.CIR-16-0362