TargetMol

TENM2 Protein, Human, Recombinant (His)

Product Code:
 
TAR-TMPK-01395
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-01395-100ug100ugEnquire
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TAR-TMPK-01395-1mg1mgEnquire
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TAR-TMPK-01395-500ug500ugEnquire
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosophila pair-rule gene ten-m/odz, is revealed to be a membrane-bound transcription regulator. In the nucleus, the intracellular domain of teneurin-2 colocalizes with promyelocytic leukemia (PML) protein in nuclear bodies implicated in transcription control.
Molecular Weight:
48.48 kDa (predicted). The protein cleaved to 55-65 kDa, 38-43 kDa and 25-30 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Bagutti C, et al. The intracellular domain of teneurin-2 has a nuclear function and represses zic-1-mediated transcription. J Cell Sci. 2003 Jul 15;116(Pt 14):2957-66. doi: 10.1242/jcs.00603. Epub 2003 Jun 3. PMID: 12783990. 2.Tucker RP, et al. Teneurin-2 is expressed in tissues that regulate limb and somite pattern formation and is induced in vitro and in situ by FGF8. Dev Dyn. 2001 Jan;220(1):27-39. doi: 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1084>3.0.CO;2-B. PMID: 11146505.